Article
Obesity-insulin targeted genes in the 3p26-25 region in human studies and LG/J and SM/J mice.
Metabolism: clinical and experimental - 1 Aug 2012
Kraja Aldi T, Lawson Heather A, Arnett Donna K, Borecki Ingrid B, Broeckel Ulrich, de las Fuentes Lisa, Hunt Steven C, Province Michael A, Cheverud James, Rao D C
Abstract excerpt
Identifying metabolic syndrome (MetS) genes is important for novel drug development and health care. This study extends the findings on human chromosome 3p26-25 for an identified obesity-insulin factor QTL, with an LOD score above 3. A focused association analysis comprising up to 9578 African American and Caucasian subjects from the HyperGEN Network (908 African Americans and 1025 whites), the Family Heart Study...
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