Article
QTL analysis of dietary obesity in C57BL/6byj X 129P3/J F2 mice: diet- and sex-dependent effects.
PloS one - 1 Jan 2013
Lin Cailu, Theodorides Maria L, McDaniel Amanda H, Tordoff Michael G, Zhang Qinmin, Li Xia, Bosak Natalia, Bachmanov Alexander A, Reed Danielle R
Abstract excerpt
Obesity is a heritable trait caused by complex interactions between genes and environment, including diet. Gene-by-diet interactions are difficult to study in humans because the human diet is hard to control. Here, we used mice to study dietary obesity genes, by four methods. First, we bred 213 F2 mice from strains that are susceptible [C57BL/6ByJ (B6)] or resistant [129P3/J (129)] to dietary obesity. Percent...
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