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Article

p53 Mutations in human cholangiocarcinoma: a review.

Liver international : official journal of the International Association for the Study of the Liver - 1 Aug 2005

Khan Shahid A, Thomas Howard C, Toledano Mireille B, Cox I Jane, Taylor-Robinson Simon D

Abstract excerpt

The reported mortality from intrahepatic bile duct tumours is increasing markedly in industrialised countries, for reasons that remain unknown. Inactivation of the tumour suppressor gene p53, is the commonest genetic abnormality in human cancer and has been implicated in the genesis of cholangiocarcinoma in various immunohistochemical and molecular epidemiological investigations, including gene sequencing...

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Share to Bile Duct Neoplasms
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15998419
DOI: 10.1111/j.1478-3231.2005.01106.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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