Article
No association between common variations in the neuronal nicotinic acetylcholine receptor alpha2 subunit gene (CHRNA2) and bipolar I disorder.
Psychiatry research - 30 Jun 2005
Lohoff Falk W, Ferraro Thomas N, McNabb Leilah, Schwebel Candice, Dahl John P, Doyle Glenn A, Buono Russell J, Berrettini Wade H
Abstract excerpt
The neuronal nicotinic acetylcholine receptor alpha2 subunit gene (CHRNA2) maps to the bipolar susceptibility locus on chromosome 8p21-22. Given the biological role of the neuronal nicotinic acetylcholine receptors and the substantial comorbidity of nicotine dependence in psychiatric disorders, the CHRNA2 gene is a plausible candidate gene for bipolar disorder (BPD). We tested the hypothesis that variations in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
