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Article

A single nucleotide polymorphism in the MDM2 gene: from a molecular and cellular explanation to clinical effect.

Cancer research - 1 Jul 2005

Bond Gareth L, Hu Wenwei, Levine Arnold

Abstract excerpt

In a recent article, a candidate pathway approach was taken to try to identify single nucleotide polymorphisms (SNP) that make up the genetic variation, which underlies the phenotypic variation seen between individuals in their susceptibility to cancer and the progression of their disease. The p53 stress response pathway was chosen given its well-documented importance in tumor suppression. A SNP was found which...

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Source

Identifiers

PMID: 15994915
DOI: 10.1158/0008-5472.CAN-05-0825

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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