Article
Nuclear localization of HIV type 1 Vif isolated from a long-term asymptomatic individual and potential role in virus attenuation.
AIDS research and human retroviruses - 1 Jun 2005
Farrow Melissa A, Somasundaran Mohan, Zhang Chengsheng, Gabuzda Dana, Sullivan John L, Greenough Thomas C
Abstract excerpt
Recent reports have determined that HIV-1 Vif counteracts an innate antiviral cellular factor, Apobec3G. However, the function of Vif during HIV-1 pathogenesis remains poorly understood. To gain a better understanding of Vif function, the viral isolate from an HIV-1-infected long-term nonprogressor (LTNP) that displayed a Vif-mutant replication phenotype was studied. This LTNP has been infected since before 1983...
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