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Article

Functional and structural defects in HIV type 1 nef genes derived from pediatric long-term survivors.

AIDS research and human retroviruses - 20 Nov 2000

Geffin R, Wolf D, Müller R, Hill M D, Stellwag E, Freitag M, Sass G, Scott G B, Baur A S

Abstract excerpt

DNA sequences and three distinct in vitro functions of Nef were evaluated in a group of seven perinatally infected children. nef gene sequences obtained before and after virus culture showed that one of the five non-/slow progressors harbored a virus with large deletions. nef genes from the remaining four children were full length but contained discrete changes at a higher frequency than the rapid progressors. In...

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Identifiers

PMID: 11118071
DOI: 10.1089/08892220050195810

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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