Article
Predominance of defective proviral sequences in an HIV + long-term non-progressor.
Immunology letters - 1 Jun 1996
Schwartz D H, Viscidi R, Laeyendecker O, Song H, Ray S C, Michael N
Abstract excerpt
We examined the accessory genes and envelope V3 region of provirus obtained over a 5 year period from an HIV+ long-term non-progressor with very low viral load and no in vitro recoverable virus during that same time span. LTR sequences supported normal Tat-mediated promoter activity. Multiple clones of nef sequences were highly conserved with < 10% containing frame shift or stop codon mutations. Functional...
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