Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional conservation of HIV-1 Vpr and variability in a mother-child pair of long-term non-progressors.

Virus research - 1 Oct 2002

Zhao Yuqi, Chen Mingzhong, Wang Bin, Yang June, Elder Robert T, Song Xiang-qian, Yu Min, Saksena Nitin K

Abstract excerpt

Increasing evidence suggests that HIV-1 Vpr is required in vivo for viral pathogenesis. Since Vpr displays multiple activities, little is known about which Vpr-specific activities are conserved in naturally occurring viruses or how natural mutations in Vpr might modulate viral pathogenesis in HIV...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Death
Share to G2 Phase
Share to Gene Products, vpr

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HeLa Cells

Share to HIV Long-Term Survivors

Share to Infectious Disease Transmission, Vertical

Share to Schizosaccharomyces

Share to vpr Gene Products, Human Immunodeficiency Virus

Source

Identifiers

PMID: 12367754
DOI: 10.1016/s0168-1702(02)00127-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12367754-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional conservation of HIV-1 Vpr and variability in a mother-child pair of long-term non-progressors.PMID 12367754Read ↗

Gene defects clustered at the C-terminus of the vpr gene of HIV-1 in long-term nonprogressing mother and child pair: in vivo evolution of vpr quasispecies in blood and plasma.Semantic proximity Read ↗

Impaired nuclear import and viral incorporation of Vpr derived from a HIV long-term non-progressorSemantic proximity Read ↗

Characterization of the molecular determinants of primary HIV-1 Vpr proteins: impact of the Q65R and R77Q substitutions on Vpr functions.Semantic proximity Read ↗

HIV-1 Vprâ€”a still â€œenigmatic multitaskerâ€Semantic proximity Read ↗

HIV1-viral protein R (Vpr) mutations: associated phenotypes and relevance for clinical pathologies.Semantic proximity Read ↗

Genetic characterization of natural variants of Vpu from HIV-1 infected individuals from Northern India and their impact on virus release and cell death.Semantic proximity Read ↗

The Role of Vpr in HIV-1 PathogenesisSemantic proximity Read ↗

Vpr and HIV-1 disease progression: R77Q mutation is associated with long-term control of HIV-1 infection in different groups of patients.Semantic proximity Read ↗

Vpr R36w and R77Q Mutations Alter HIV-1 Replication and Cytotoxicity in T LymphocytesSemantic proximity Read ↗

Comparison of proviral accessory genes between long-term nonprogressors and progressors of human immunodeficiency virus type 1 infection.Semantic proximity Read ↗

HIV-1 Accessory Protein Vpr: Relevance in the pathogenesis of HIV and potential for therapeutic interventionSemantic proximity Read ↗

An Observational Study of Genetic Diversity of HIV-1 vpu in Rapid Progressors in India.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.