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Article

The multiple functions of Tamm-Horsfall protein in human health and disease: a mystery clears up.

Wiener klinische Wochenschrift - 1 May 2005

Weichhart Thomas, Zlabinger Gerhard J, Säemann Marcus D

Abstract excerpt

Tamm-Horsfall protein (THP) is exclusively produced by renal tubular cells of the distal loop of Henle and is the most abundant urinary protein in mammals. The physiological function of THP has remained elusive for over half a century; however, new lines of research position it as a central antimicrobial molecule combating urinary tract infection (UTI). Furthermore, the genetic basis of familial juvenile...

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Identifiers

PMID: 15989109
DOI: 10.1007/s00508-005-0353-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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