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Article

Tamm-Horsfall glycoprotein: biology and clinical relevance.

American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Oct 2003

Serafini-Cessi Franca, Malagolini Nadia, Cavallone Daniela

Abstract excerpt

Tamm-Horsfall glycoprotein (THP) is the most abundant urinary protein in mammals. Urinary excretion occurs by proteolytic cleavage of the large ectodomain of the glycosyl phosphatidylinositol-anchored counterpart exposed at the luminal cell surface of the thick ascending limb of Henle's loop. We describe the physical-chemical structure of human THP and its biosynthesis and interaction with other proteins and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14520616
DOI: 10.1016/s0272-6386(03)00829-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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