Genetic epidemiology of early onset breast cancer.

doi:10.1136/jmg.31.12.944

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Article

Genetic epidemiology of early onset breast cancer.

Journal of medical genetics - 1 Dec 1994

Eccles D, Marlow A, Royle G, Collins A, Morton N E

Abstract excerpt

Risks for breast cancer when there is a family history of the disease are usually calculated using data from segregation analyses which favour a single dominant gene with high penetrance. There are, however, at least three loci known to be associated with familial breast cancer (p53, BRCA1, and a...

Topics

Adult
Age of Onset
Aged
Aged, 80 and over
Breast Neoplasms
Female
Genotype
Humans
Middle Aged
Pedigree
Risk Factors
United Kingdom

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