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Article

Differential recognition of response elements determines target gene specificity for p53 and p63.

Molecular and cellular biology - 1 Jul 2005

Osada Motonobu, Park Hannah Lui, Nagakawa Yuichi, Yamashita Keishi, Fomenkov Alexey, Kim Myoung Sook, Wu Guojun, Nomoto Shuji, Trink Barry, Sidransky David

Abstract excerpt

p63 is a member of the p53 tumor suppressor gene family, which regulates downstream target gene expression by binding to sequence-specific response elements similar to those of p53. By using oligonucleotide expression microarray analysis and analyzing the promoters of p63-induced genes, we have identified novel p63-specific response elements (p63-REs) in the promoter regions of EVPL and SMARCD3. These p63-REs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15988020
DOI: 10.1128/MCB.25.14.6077-6089.2005
PMCID: PMC1168821

Genes

EVPL
SMARCD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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