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Article

Differential effects of p63 mutants on transactivation of p53 and/or p63 responsive genes.

Cell research - 1 Oct 2008

Khokhar Shama K, Kommagani Ramakrishna, Kadakia Madhavi P

Abstract excerpt

p63, known to play a role in development, has more recently also been implicated in cancer progression. Mutations in p63 have been shown to be responsible for several human developmental diseases. Differential splicing of the p63 gene gives rise to p63 isoforms, which can act either as tumor suppressors or as oncogene. In this report, we studied the effects of naturally occurring TAp63gamma mutants on the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18626511
DOI: 10.1038/cr.2008.82
PMCID: PMC2760224

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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