Article
Natural controlled HIV infection: preserved HIV-specific immunity despite undetectable replication competent virus.
Virology - 15 Aug 2005
Kloosterboer Nico, Groeneveld Paul H P, Jansen Christine A, van der Vorst Teun J K, Koning Fransje, Winkel Carel N, Duits Ashley J, Miedema Frank, van Baarle Debbie, van Rij Ronald P, Brinkman Kees, Schuitemaker Hanneke
Abstract excerpt
Long-term non-progressive HIV infection, characterized by low but detectable viral load and stable CD4 counts in the absence of antiviral therapy, is observed in about 5% of HIV-infected patients. Here we identified four therapy naïve individuals who are strongly seropositive for HIV-1 but who lack evidence of detectable HIV p24 antigen, plasma RNA, and proviral DNA in routine diagnostic testing. With an...
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