Article

Prolonged non-suppressible viremia sustained by a clonally expanded, genomically defective provirus with an immune-evasive HIV protein expression profile

2025-05-16

Abstract excerpt

Antiretroviral therapy (ART) potently inhibits HIV replication but does not eliminate HIV proviruses integrated within the genomes of infected cells. Though ART normally suppresses HIV to clinically undetectable levels in blood, some individuals experience non-suppressible viremia (NSV) that is not attributable to suboptimal drug exposure ( e.g. due to incomplete medication adherence or pharmacological issues) no...

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Literature Corpus work: 05cddd40-2caa-51a3-be4f-0fe8594b46e4
DOI: 10.1101/2025.05.16.654538

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