Article
Immunological profile of heterosexual highly HIV-exposed uninfected individuals: predominant role of CD4 and CD8 T-cell activation.
The Journal of infectious diseases - 15 Oct 2007
Suy Anna, Castro Pedro, Nomdedeu Meritxell, García Felipe, López Anna, Fumero Emilio, Gallart Teresa, Lopalco Lucia, Coll Oriol, Gatell José M, Plana Montserrat
Abstract excerpt
BACKGROUND: Altered T cell subset distribution patterns in uninfected individual highly exposed to human immunodeficiency virus (HIV) have been explained either as a consequence of viral exposure or as a surrogate marker of low susceptibility to infection. METHODS: Multiple genetic and immunological parameters were studied prospectively in 21 HIV-serodiscordant heterosexual couples. RESULTS: We found changes of...
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