Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The CYP17 MspA1 polymorphism and breast cancer risk: a meta-analysis.

Mutagenesis - 1 Mar 2002

Ye Zheng, Parry James M

Abstract excerpt

Inter-individual differences in susceptibility to breast cancer are partially mediated through the levels of endogenous and exogenous steroid hormones. The CYP17 gene encodes P450c17alpha, an enzyme that is involved in the metabolism of steroid hormones. Increased endogenous steroid hormone levels have been associated with a MspA1 polymorphism in the 5'-promoter region of the CYP17 gene. The CYP17 MspA1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Breast Neoplasms
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Susceptibility

Share to Homozygote

Share to Menarche

Share to Odds Ratio

Share to Steroid 17-alpha-Hydroxylase

Source

Identifiers

PMID: 11880540
DOI: 10.1093/mutage/17.2.119

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The CYP17 MspA1 polymorphism and breast cancer risk: a meta-analysis.PMID 11880540Read ↗

CYP17 and breast cancer: no overall effect, but what about interactions?Semantic proximity Read ↗

Lack of association between CYP17 MspA1 polymorphism and breast cancer risk: a meta-analysis of 22,090 cases and 28,498 controls.Semantic proximity Read ↗

CYP17 5'-UTR MspA1 polymorphism and the risk of premenopausal breast cancer in a German population-based case-control study.Semantic proximity Read ↗

CYP17 genetic polymorphism, breast cancer, and breast cancer risk factors.Semantic proximity Read ↗

Genetic polymorphism of CYP17 and breast cancer risk in Korean women.Semantic proximity Read ↗

CYP17 genotype and breast cancer risk.Semantic proximity Read ↗

CYP17 genetic polymorphism, breast cancer, and breast cancer risk factors: Australian Breast Cancer Family Study.Semantic proximity Read ↗

Cytochrome P4501A1 polymorphism as a susceptibility factor for breast cancer in postmenopausal Chinese women in Taiwan.Semantic proximity Read ↗

Steroid metabolism gene CYP17 polymorphism and the development of breast cancer.Semantic proximity Read ↗

The CYP17A1 -34T > C polymorphism and breast cancer risk in BRCA1 and BRCA2 mutation carriers.Semantic proximity Read ↗

Association between CYP17 polymorphisms and the development of breast cancer.Semantic proximity Read ↗

CYP17 and SULT1A1 gene polymorphisms in Indian breast cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.