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A polymorphism in the CYP17 gene increases the risk of breast cancer.

Cancer research - 15 Mar 1997

Feigelson H S, Coetzee G A, Kolonel L N, Ross R K, Henderson B E

Abstract excerpt

We conducted a case-control study to determine whether a polymorphism in the CYP17 gene was associated with risk of breast cancer. We found an increased risk of advanced breast cancer in women carrying an A2 allele. The odds ratio was 2.5 [95% confidence interval (CI), 1.07-5.94] for regional or...

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Genotype
Aged
Polymorphism, Genetic
Case-Control Studies
Breast Neoplasms
Disease Susceptibility

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PMID: 9067272

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-9067272-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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