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Lack of association between CYP17 MspA1 polymorphism and breast cancer risk: a meta-analysis of 22,090 cases and 28,498 controls.

Breast cancer research and treatment - 1 Jul 2010

Mao Chen, Wang Xi-Wen, He Ben-Fu, Qiu Li-Xin, Liao Ru-Yan, Luo Rong-Cheng, Chen Qing

Abstract excerpt

Epidemiological studies have evaluated the association between CYP17 MspA1 polymorphism and breast cancer risk. However, the results remain conflicting rather than conclusive. To derive a more precise estimation of the relationship, we performed this meta-analysis. Systematic searches of the PubMed and Medline databases were performed. A total of 35 studies including 22,090 cases and 28,498 controls were...

Topics

Amino Acid Substitution
Breast Neoplasms
Case-Control Studies
Ethnicity
Female
Genetic Predisposition to Disease
Genotype
Humans
Menopause
Models, Genetic
Odds Ratio

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Patient Selection

Polymorphism, Restriction Fragment Length

Polymorphism, Single Nucleotide

Risk

Steroid 17-alpha-Hydroxylase

Source

Identifiers

PMID: 20033766
DOI: 10.1007/s10549-009-0695-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Lack of association between CYP17 MspA1 polymorphism and breast cancer risk: a meta-analysis of 22,090 cases and 28,498 controls.PMID 20033766Read ↗

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