Article
Bipartite structure of the downstream element of the mouse beta globin (major) poly(A) signal.
Nucleic acids research - 25 May 1992
Chen J S, Nordstrom J L
Abstract excerpt
The downstream region of the mouse beta (major) globin poly(A) signal was mutated and analyzed for function in transfected COS cells. From analysis of unidirectional Bal31 deletions, the 3' boundary of the downstream element was defined as +22 (22 nucleotides downstream from the cleavage site). Analysis of cluster mutations, in which 5 or 6 adjacent bases were replaced with a random CA-containing sequence in a...
Topics
- Animals
- Base Sequence
- DNA Mutational Analysis
- Globins
- Mice
- Mice, Inbred BALB C
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- Oligodeoxyribonucleotides
- Plasmids
- Poly A