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Article

The promoter and 5' flanking sequences controlling human B29 gene expression

15 Jan 1996

Abstract excerpt

The product of the B-cell-specific B29 gene (B29, Ig beta, CD79b) is essential for Ig-mediated B-cell activation via the B-cell antigen receptor complex (BCR) on human and murine B lymphocytes. To better understand the regulation of this pivotal gene, we have analyzed the human genomic DNA sequence upstream of the B29 ATG start codon for transcriptional control activity. The human B29 gene lacks either a TATA or...

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Identifiers

PMID: 8555489
DOI: 10.1182/blood.v87.2.666.bloodjournal872666

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