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Article

Upstream sequence elements enhance poly(A) site efficiency of the C2 complement gene and are phylogenetically conserved.

The EMBO journal - 1 Aug 1995

Moreira A, Wollerton M, Monks J, Proudfoot N J

Abstract excerpt

Poly(A) signals of mammalian pre-mRNA have been defined as an AAUAAA sequence 10-30 nt upstream of the cleavage/poly(A) site followed by a GU/U-rich element immediately downstream. However, a number of viral poly(A) signals have been shown to possess additional signals upstream of AAUAAA that increase poly(A) site efficiency. We describe the first non-viral example of such an upstream sequence element (USE) for...

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Identifiers

PMID: 7641699
DOI: 10.1002/j.1460-2075.1995.tb00050.x
PMCID: PMC394455

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Upstream sequence elements enhance poly(A) site efficiency of the C2 complement gene and are phylogenetically conserved.PMID 7641699Read ↗

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