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Article

Genetic control of parasite clearance leads to resistance to Plasmodium berghei ANKA infection and confers immunity.

Genes and immunity - 1 Aug 2005

Campino S, Bagot S, Bergman M-L, Almeida P, Sepúlveda N, Pied S, Penha-Gonçalves C, Holmberg D, Cazenave P-A

Abstract excerpt

Unprecedented cure after infection with the lethal Plasmodium berghei ANKA was observed in an F2 progeny generated by intercrossing the wild-derived WLA and the laboratory C57BL/6 mouse strains. Resistant mice were able to clear parasitaemia and establish immunity. The observed resistance was disclosed as a combinatorial effect of genetic factors derived from the two parental strains. Genetic mapping of survival...

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PMID: 15973462
DOI: 10.1038/sj.gene.6364219

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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