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Article

Listeria-infected myeloid dendritic cells produce IFN-beta, priming T cell activation.

Journal of immunology (Baltimore, Md. : 1950) - 1 Jul 2005

Feng Hanping, Zhang Dong, Palliser Deborah, Zhu Pengcheng, Cai Shenghe, Schlesinger Ann, Maliszewski Laura, Lieberman Judy

Abstract excerpt

The intracellular bacterium Listeria monocytogenes infects dendritic cells (DC) and other APCs and induces potent cell-mediated protective immunity. However, heat-killed bacteria fail to do so. This study explored whether DC differentially respond to live and killed Listeria and how this affects T cell activation. To control for bacterial number, a replication-deficient strain, Lmdd, defective in D-alanine...

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Share to Antigens, Differentiation, T-Lymphocyte
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dendritic Cells

Share to Interferon-beta

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Share to Receptors, Antigen, T-Cell

Source

Identifiers

PMID: 15972676
DOI: 10.4049/jimmunol.175.1.421

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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