Article
Listeria monocytogenes multidrug resistance transporters activate a cytosolic surveillance pathway of innate immunity.
Proceedings of the National Academy of Sciences of the United States of America - 22 Jul 2008
Crimmins Gregory T, Herskovits Anat A, Rehder Kai, Sivick Kelsey E, Lauer Peter, Dubensky Thomas W, Portnoy Daniel A
Abstract excerpt
To gain insight into the interaction of intracellular pathogens with host innate immune pathways, we performed an unbiased genetic screen of Listeria monocytogenes mutants that induced an enhanced or diminished host innate immune response. Here, we show that the major facilitator superfamily of b...
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