Article
Listeria monocytogenes-infected human dendritic cells: uptake and host cell response.
Infection and immunity - 1 Jun 2000
Kolb-Mäurer A, Gentschev I, Fries H W, Fiedler F, Bröcker E B, Kämpgen E, Goebel W
Abstract excerpt
Dendritic cells (DCs) are potent antigen-presenting cells and play a crucial role in initiation and modulation of specific immune responses. Various pathogens are able to persist inside DCs. However, internalization of the gram-positive bacterium Listeria monocytogenes into human DCs has not yet been shown. In the present study, we demonstrate that human monocyte-derived immature DCs can efficiently phagocytose...
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