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Article

Characterization of the interferon-producing cell in mice infected with Listeria monocytogenes.

PLoS pathogens - 1 Mar 2009

Stockinger Silvia, Kastner Renate, Kernbauer Elisabeth, Pilz Andreas, Westermayer Sandra, Reutterer Benjamin, Soulat Didier, Stengl Gabriele, Vogl Claus, Frenz Theresa, Waibler Zoe, Taniguchi Tadatsugu, Rülicke Thomas, Kalinke Ulrich, Müller Mathias, Decker Thomas

Abstract excerpt

Production of type I interferons (IFN-I, mainly IFNalpha and IFNbeta) is a hallmark of innate immune responses to all classes of pathogens. When viral infection spreads to lymphoid organs, the majority of systemic IFN-I is produced by a specialized "interferon-producing cell" (IPC) that has been shown to belong to the lineage of plasmacytoid dendritic cells (pDC). It is unclear whether production of systemic...

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Source

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Identifiers

PMID: 19325882
DOI: 10.1371/journal.ppat.1000355
PMCID: PMC2654726

Genes

TLR9

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Source receipt: pubmed, retrieved 7 Sept 2026.

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