Article
Bacterial infection alters the kinetics and function of iNKT cell responses.
Journal of leukocyte biology - 1 Dec 2008
Choi Hak-Jong, Xu Honglin, Geng Yanbiao, Colmone Angela, Cho Hoonsik, Wang Chyung-Ru
Abstract excerpt
CD1d-restricted Valpha14 invariant NKT cells (iNKT) are innate-like, immunoregulatory lymphocytes that play critical roles in autoimmunity, tumor surveillance, and infectious disease. Although iNKT cells are activated during microbial infection, the impacts of infection on the function of iNKT cells have not been fully characterized. Using a Listeria monocytogenes (LM) infection model, we found that iNKT cells...
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