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Article

Centrin 2 stimulates nucleotide excision repair by interacting with xeroderma pigmentosum group C protein.

Molecular and cellular biology - 1 Jul 2005

Nishi Ryotaro, Okuda Yuki, Watanabe Eriko, Mori Toshio, Iwai Shigenori, Masutani Chikahide, Sugasawa Kaoru, Hanaoka Fumio

Abstract excerpt

Xeroderma pigmentosum group C (XPC) protein plays a key role in DNA damage recognition in global genome nucleotide excision repair (NER). The protein forms in vivo a heterotrimeric complex involving one of the two human homologs of Saccharomyces cerevisiae Rad23p and centrin 2, a centrosomal protein. Because centrin 2 is dispensable for the cell-free NER reaction, its role in NER has been unclear. Binding...

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Identifiers

PMID: 15964821
DOI: 10.1128/MCB.25.13.5664-5674.2005
PMCID: PMC1156980

Genes

XPC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Centrin 2 stimulates nucleotide excision repair by interacting with xeroderma pigmentosum group C protein.PMID 15964821Read ↗

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