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Article

Overview of xeroderma pigmentosum proteins architecture, mutations and post-translational modifications.

Mutation research. Reviews in mutation research - 1 Jan 2000

Feltes Bruno César, Bonatto Diego

Abstract excerpt

The xeroderma pigmentosum complementation group proteins (XPs), which include XPA through XPG, play a critical role in coordinating and promoting global genome and transcription-coupled nucleotide excision repair (GG-NER and TC-NER, respectively) pathways in eukaryotic cells. GG-NER and TC-NER are both required for the repair of bulky DNA lesions, such as those induced by UV radiation. Mutations in genes that...

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Source

Identifiers

PMID: 25795128
DOI: 10.1016/j.mrrev.2014.12.002

Genes

XPA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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