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Article

The role of XPC: implications in cancer and oxidative DNA damage.

Mutation research - 1 Jan 2000

Melis Joost P M, Luijten Mirjam, Mullenders Leon H F, van Steeg Harry

Abstract excerpt

The accumulation of DNA damage is a slow but hazardous phenomenon that may lead to cell death, accelerated aging features and cancer. One of the most versatile and important defense mechanisms against the accumulation of DNA damage is nucleotide excision repair (NER), in which the Xeroderma pigmentosum group C (XPC) protein plays a prominent role. NER can be divided into global genome repair (GG-NER) and...

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Source

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Identifiers

PMID: 21763452
DOI: 10.1016/j.mrrev.2011.07.001
PMCID: PMC3203325

Genes

XPC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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