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Article

SCL/TAL1 expression level regulates human hematopoietic stem cell self-renewal and engraftment.

Blood - 1 Oct 2005

Reynaud Damien, Ravet Emmanuel, Titeux Monique, Mazurier Frédéric, Rénia Laurent, Dubart-Kupperschmitt Anne, Roméo Paul-Henri, Pflumio Françoise

Abstract excerpt

The fate of hematopoietic stem cells (HSCs) is regulated through a combinatorial action of proteins that determine their self-renewal and/or their commitment to differentiation. Stem cell leukemia/T-cell acute lymphoblastic leukemia 1 (SCL/TAL1), a basic helix-loop-helix (bHLH) transcription factor, plays key roles in controlling the development of primitive and definitive hematopoiesis during mouse development...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15961517
DOI: 10.1182/blood-2005-02-0557

Genes

TAL1
SRC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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SCL/TAL1 expression level regulates human hematopoietic stem cell self-renewal and engraftment.PMID 15961517Read ↗

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