Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene expression signatures for colorectal cancer microsatellite status and HNPCC

24 May 2005

Abstract excerpt

The majority of microsatellite instable (MSI) colorectal cancers are sporadic, but a subset belongs to the syndrome hereditary non-polyposis colorectal cancer (HNPCC). Microsatellite instability is caused by dysfunction of the mismatch repair (MMR) system that leads to a mutator phenotype, and MSI is correlated to prognosis and response to chemotherapy. Gene expression signatures as predictive markers are being...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Colorectal Cancer Screening and Detection
Share to Genetic factors in colorectal cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15956967
DOI: 10.1038/sj.bjc.6602621

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene expression signatures for colorectal cancer microsatellite status and HNPCCPMID 15956967Read ↗

A robust genomic signature for the detection of colorectal cancer patients with microsatellite instability phenotype and high mutation frequency.Semantic proximity Read ↗

Gene expression differences among different MSI statuses in colorectal cancer.Semantic proximity Read ↗

A Gene Expression Signature of Genetic Instability in Colon CancerSemantic proximity Read ↗

DNA Copy-Number Alterations Underlie Gene Expression Differences between Microsatellite Stable and Unstable Colorectal CancersSemantic proximity Read ↗

Transcriptome and Network Dissection of Microsatellite Stable and Highly Instable Colorectal CancerSemantic proximity Read ↗

mRNA/microRNA gene expression profile in microsatellite unstable colorectal cancerSemantic proximity Read ↗

Prognostic significance and gene expression profiles of p53 mutations in microsatellite-stable stage III colorectal adenocarcinomas.Semantic proximity Read ↗

Molecular pathways: microsatellite instability in colorectal cancer: prognostic, predictive, and therapeutic implications.Semantic proximity Read ↗

The ATOM-Seq sequence capture panel can accurately predict microsatellite instability status in formalin-fixed tumour samples, alongside routine gene mutation testing.Semantic proximity Read ↗

Gene expression variations in microsatellite stable and unstable colon cancer cells.Semantic proximity Read ↗

A novel NGS-based microsatellite instability (MSI) status classifier with 9 loci for colorectal cancer patients.Semantic proximity Read ↗

PreMSIm: An R package for predicting microsatellite instability from the expression profiling of a gene panel in cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.