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Article

CYP3A5 genotype is associated with diagnosis of hypertension in elderly patients: data from the DEBATE Study.

American journal of pharmacogenomics : genomics-related research in drug development and clinical practice - 1 Jan 2005

Kivistö Kari T, Niemi Mikko, Schaeffeler Elke, Pitkälä Kaisu, Tilvis Reijo, Fromm Martin F, Schwab Matthias, Lang Florian, Eichelbaum Michel, Strandberg Timo

Abstract excerpt

OBJECTIVE: The aim of this study was to address the presently controversial question of whether cytochrome P450 (CYP) 3A5 polymorphism is associated with hypertension. METHOD: We studied 373 elderly (age > or =75 years) Finnish (Caucasian) patients from the ongoing DEBATE (Drugs and Evidence Based Medicine in the Elderly) trial. The patients were classified into those with a history of hypertension (n = 229) and...

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Source

Identifiers

PMID: 15952872
DOI: 10.2165/00129785-200505030-00005

Genes

ABCB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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