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CYP3A5 genotype has significant effect on quinine 3-hydroxylation in Tanzanians, who have lower total CYP3A activity than a Swedish population.

Pharmacogenetics and genomics - 1 Sept 2006

Mirghani Rajaa A, Sayi Jane, Aklillu Eleni, Allqvist Annika, Jande Mary, Wennerholm Agneta, Eriksen Jaran, Herben Virginie M M, Jones Barry C, Gustafsson Lars L, Bertilsson Leif

Abstract excerpt

OBJECTIVES: To study the correlation between CYP3A5 genotype and quinine 3-hydroxylation in black Tanzanian and Swedish Caucasians as well as to investigate the interethnic differences in CYP3A activity between the two populations. METHODS: Tanzanian (n=144) and Swedish (n=136) healthy study part...

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PMID: 16906018
DOI: 10.1097/01.fpc.0000230411.89973.1b

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16906018-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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