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Article

Warfarin dose related to apolipoprotein E (APOE) genotype.

European journal of clinical pharmacology - 1 Jul 2005

Kohnke Hugo, Sörlin Kristina, Granath Göran, Wadelius Mia

Abstract excerpt

OBJECTIVE: Warfarin is an anticoagulant which acts through interference with the recycling of vitamin K in the liver, leading to reduced activation of several clotting factors. Apolipoprotein E plays a central role in the uptake of the lipid-soluble vitamin K. The apolipoprotein E (APOE) alleles E2, E3 and E4 encode the three major isoforms of apolipoprotein E. The aim of this project was to evaluate whether...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15952022
DOI: 10.1007/s00228-005-0936-3

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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