Article
Apolipoprotein E genotype affects plasma lipid response to atorvastatin in a gender specific manner.
Atherosclerosis - 1 Sept 2001
Pedro-Botet J, Schaefer E J, Bakker-Arkema R G, Black D M, Stein E M, Corella D, Ordovas J M
Abstract excerpt
The response to therapy with hypolipidemic agents shows considerable individual variation. These differences may be due to the interaction of environmental and genetic factors that affect drug bioavailability, receptor function or ligand structure. Our objective was to assess the effect of apolipoprotein (apo) E genotype and gender on lipid-lowering response to the HMG CoA reductase inhibitor, atorvastatin....
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