Article
MnSOD polymorphisms in sensitized patients with delayed-type hypersensitivity reactions to the chemical allergen para-phenylene diamine: a case-control study.
Toxicology - 1 Sept 2005
Brans Richard, Dickel Heinrich, Bruckner Thomas, Coenraads Pieter-Jan, Heesen Michael, Merk Hans F, Blömeke Brunhilde
Abstract excerpt
Dyes such as para-phenylene diamine (PPD) or related para-compounds are very common contact sensitizers in man. The corresponding contact dermatitis in sensitized individuals is a complex and common illness associated with considerable morbidity and social cost. It has been found that oxidative stress from reactive oxygen species (ROS) may play an important role in the pre-immunological phase of allergic contact...
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