Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between TNFA-308 G/A polymorphism and sensitization to para-phenylenediamine: a case-control study.

Allergy - 1 Feb 2009

Blömeke B, Brans R, Dickel H, Bruckner T, Erdmann S, Heesen M, Merk H F, Coenraads P-J

Abstract excerpt

BACKGROUND: Para-phenylenediamine (PPD) and related chemicals are common contact sensitizers, frequently causing allergic contact dermatitis (ACD). The cytokine tumor necrosis factor-alpha (TNF-alpha) plays a key role in contact sensitization. METHODS: In this case-control study, we evaluated the distribution of variations in the regulatory region of the gene for TNF-alpha (TNFA-308 G/A) in 181 Caucasian...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Coloring Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dermatitis, Allergic Contact

Share to Gene Frequency

Share to Logistic Models

Share to Phenylenediamines

Share to Polymorphism, Genetic

Share to Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 18384449
DOI: 10.1111/j.1398-9995.2008.01704.x

Genes

ACD
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between TNFA-308 G/A polymorphism and sensitization to para-phenylenediamine: a case-control study.PMID 18384449Read ↗

Genetic susceptibility to occupational contact dermatitis.Semantic proximity Read ↗

Impact of tumour necrosis factor-α polymorphisms on irritant contact dermatitis.Semantic proximity Read ↗

Immunology and genetics of tumour necrosis factor in allergic contact dermatitis.Semantic proximity Read ↗

Association of TNFA gene polymorphism at position -308 with susceptibility to irritant contact dermatitis.Semantic proximity Read ↗

Cytokine gene polymorphisms in allergic contact dermatitis.Semantic proximity Read ↗

Genetic endowment of proinflammatory cytokine tumor necrosis factor-α (-) 308 G > A polymorphism to Parthenium hysterophorus-induced airborne contact dermatitis in an Indian cohort.Semantic proximity Read ↗

Association of tumor necrosis factor-alpha -308G>A polymorphism with IgE-mediated allergy to betalactams in an Italian population.Semantic proximity Read ↗

MnSOD polymorphisms in sensitized patients with delayed-type hypersensitivity reactions to the chemical allergen para-phenylene diamine: a case-control study.Semantic proximity Read ↗

Genetic variants in TNFα, TGFB1, PTGS1 and PTGS2 genes are associated with diisocyanate-induced asthma.Semantic proximity Read ↗

Tumor necrosis factor (TNF)-α -308G/A (rs1800629) polymorphism distribution in North India and its association with pemphigus: Case-control study and meta-analysis.Semantic proximity Read ↗

Cytokine gene polymorphisms and susceptibility to chronic irritant contact dermatitis.Semantic proximity Read ↗

Role of Interleukin-4, Interleukin-10, and Tumor Necrosis Factor-α Polymorphic Genes in the Pathogenesis of Occupational Allergic Dermatoses.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.