Article
Assessment of urinary aromatic amines in Brazilian pregnant women and association with DNA damage: Influence of genetic diversity, lifestyle, and environmental and socioeconomic factors.
Environmental pollution (Barking, Essex : 1987) - 15 Oct 2023
Souza Marília Cristina Oliveira, González Neus, Rovira Joaquim, Herrero Marta, Marquès Montse, Nadal Martí, Barbosa Fernando, Domingo José Luis
Abstract excerpt
Aromatic amines (AAs) are polar organic chemicals with a wide environmental distribution originating from various sources, such as tobacco smoke, diesel exhaust, and dermal absorption from textile products with azo dyes. The toxicity profile of AAs is directly related to the amino group's metabolic activation and the generation of the reactive intermediate, forming DNA adducts and potential carcinogenicity....
Topics
- Pregnancy
- Humans
- Female
- Tobacco Smoke Pollution
- Pregnant People
- 8-Hydroxy-2'-Deoxyguanosine
- Brazil
- Placenta
- Aniline Compounds
- Amines
- DNA Damage
- Smoke
- Azo Compounds