Article
Analysis of Manganese Superoxide Dismutase and Glutathione Peroxidase 1 Gene Polymorphisms in Vitiligo.
Biochemical genetics - 1 Aug 2016
Seçkin Havva Yıldız, Kalkan Göknur, Bütün İlknur, Akbaş Ali, Baş Yalçın, Karakuş Nevin, Benli İsmail
Abstract excerpt
Vitiligo is a hereditary/acquired progressive pigmentation disorder characterized by discoloration of skin as a result of melanocyte dysfunction. Recent studies have proposed that oxidant/antioxidant status plays an important role in vitiligo pathogenesis because of the toxic effects on melanocytes. In this study, we aimed to investigate possible associations of MnSOD Ala-9Val and GPx1 Pro198Leu polymorphisms...
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