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Article

Pleiotrophin induces formation of functional neovasculature in vivo.

Biochemical and biophysical research communications - 15 Jul 2005

Christman Karen L, Fang Qizhi, Kim Anne J, Sievers Richard E, Fok Hubert H, Candia Albert F, Colley Kenneth J, Herradon Gonzalo, Ezquerra Laura, Deuel Thomas F, Lee Randall J

Abstract excerpt

Pleiotrophin (PTN) is a heparin-binding growth/differentiation inducing cytokine that shares 50% amino acid sequence identity and striking domain homology with Midkine (MK), the only other member of the Ptn/Mk developmental gene family. The Ptn gene is expressed in sites of early vascular development in embryos and in healing wounds and its constitutive expression in many human tumors is associated with an...

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Source

Identifiers

PMID: 15949466
DOI: 10.1016/j.bbrc.2005.04.174

Genes

PTN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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