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Article

Thrombin induces neoangiogenesis in the chick chorioallantoic membrane.

Journal of thrombosis and haemostasis : JTH - 1 Oct 2003

Caunt M, Huang Y-Q, Brooks P C, Karpatkin S

Abstract excerpt

Most tumors have constitutively active tissue factor on their surface, capable of generating thrombin in the surrounding environment, and thrombosis is associated with cancer. Thrombin is known to induce a malignant phenotype by enhancing tissue adhesion and cell growth in vitro and in vivo in mice. Because tumors require angiogenesis for growth, we examined whether thrombin induces neoangiogenesis in a...

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Source

Identifiers

PMID: 14521590
DOI: 10.1046/j.1538-7836.2003.00426.x

Genes

KDR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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