Article
Implanted microvessels progress through distinct neovascularization phenotypes.
Microvascular research - 1 Jan 2010
Nunes Sara S, Greer Kevin A, Stiening Chad M, Chen Helen Y S, Kidd Kameha R, Schwartz Mark A, Sullivan Chris J, Rekapally Harish, Hoying James B
Abstract excerpt
We have previously demonstrated that implanted microvessels form a new microcirculation with minimal host-derived vessel investment. Our objective was to define the vascular phenotypes present during neovascularization in these implants and identify post-angiogenesis events. Morphological, functional and transcriptional assessments identified three distinct vascular phenotypes in the implants: sprouting...
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