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Article

Pleiotrophin stimulates fibroblasts and endothelial and epithelial cells and is expressed in human cancer.

1 Dec 1992

Abstract excerpt

Previously we reported the purification of the heparin-binding growth factor pleiotrophin (PTN) from supernatants of the human breast cancer cell line MDA-MB-231. To investigate further the biological activities of PTN and its potential role in cancer, we cloned a PTN cDNA and expressed the gene in a human kidney and in a human adrenal carcinoma cell line (SW-13). The supernatants harvested from cells transfected...

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Identifiers

PMID: 1464602
DOI: 10.1016/s0021-9258(18)35692-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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