Article
The Aspergillus nidulans sldI(RAD50) gene interacts with bimE(APC1), a homologue of an anaphase-promoting complex subunit.
Molecular microbiology - 1 Jul 2005
Malavazi Iran, Lima Joel Fernandes, von Zeska Kress Fagundes Márcia Regina, Efimov Vladimir P, de Souza Goldman Maria Helena, Goldman Gustavo Henrique
Abstract excerpt
The Mre11-Rad50-Nbs1 protein complex has emerged as a central component in the human cellular DNA damage response, and recent observations suggest that these proteins are at least partially responsible for the linking of DNA damage detection to DNA repair and cell cycle checkpoint functions. We have identified Aspergillus nidulans sldI1444D mutant in a screen for dynein synthetic lethals. The sldI(RAD50) gene was...
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