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Article

Aspergillus nidulans uvsBATR and scaANBS1 genes show genetic interactions during recovery from replication stress and DNA damage.

Eukaryotic cell - 1 Jul 2005

Fagundes Marcia Regina von Zeska Kress, Semighini Camile P, Malavazi Iran, Savoldi Marcela, de Lima Joel Fernandes, de Souza Goldman Maria Helena, Harris Steven D, Goldman Gustavo Henrique

Abstract excerpt

The ATM/ATR kinases and the Mre11 (Mre11-Rad50-Nbs1) protein complex are central players in the cellular DNA damage response. Here we characterize possible interactions between Aspergillus nidulans uvsB(ATR) and the Mre11 complex (scaA(NBS1)). We demonstrate that there is an epistatic relationship between uvsB(ATR), the homolog of the ATR/MEC1 gene, and scaA(NBS1), the homolog of the NBS1/XRS2 gene, for both...

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Source

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Identifiers

PMID: 16002650
DOI: 10.1128/EC.4.7.1239-1252.2005
PMCID: PMC1168959

Genes

ATR
ATM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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