Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CDC7/DBF4 functions in the translesion synthesis branch of the RAD6 epistasis group in Saccharomyces cerevisiae.

Genetics - 1 Aug 2004

Pessoa-Brandão Luis, Sclafani Robert A

Abstract excerpt

CDC7 and DBF4 encode the essential Cdc7-Dbf4 protein kinase required for DNA replication in eukaryotes from yeast to human. Cdc7-Dbf4 is also required for DNA damage-induced mutagenesis, one of several postreplicational DNA damage tolerance mechanisms mediated by the RAD6 epistasis group. Several genes have been determined to function in separate branches within this group, including RAD5, REV3/REV7 (Pol zeta),...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Cycle Proteins
Share to DNA Damage
Share to DNA Replication

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Methyl Methanesulfonate

Share to Mutagens

Share to Phosphoproteins

Share to Ubiquitin-Conjugating Enzymes

Share to Ultraviolet Rays

Source

Open in PubMed Open full text

Identifiers

PMID: 15342501
DOI: 10.1534/genetics.103.021675
PMCID: PMC1471023

Genes

CDC7
PCNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CDC7/DBF4 functions in the translesion synthesis branch of the RAD6 epistasis group in Saccharomyces cerevisiae.PMID 15342501Read ↗

Roles of RAD6 epistasis group members in spontaneous polzeta-dependent translesion synthesis in Saccharomyces cerevisiae.Semantic proximity Read ↗

The role of Dbf4-dependent protein kinase in DNA polymerase ζ-dependent mutagenesis in Saccharomyces cerevisiae.Semantic proximity Read ↗

Ddb1 controls genome stability and meiosis in fission yeast.Semantic proximity Read ↗

Cdc7 kinases (DDKs) and checkpoint responses: lessons from two yeasts.Semantic proximity Read ↗

uvsZ1 mutation shows epistatic relations with uvsD153 and uvsJ1 mutations without any involvement with checkpoint control in Aspergillus nidulans.Semantic proximity Read ↗

Synergistic interactions between RAD5, RAD16 and RAD54, three partially homologous yeast DNA repair genes each in a different repair pathway.Semantic proximity Read ↗

Involvement of budding yeast Rad5 in translesion DNA synthesis through physical interaction with Rev1.Semantic proximity Read ↗

DNA damage checkpoints are involved in postreplication repair.Semantic proximity Read ↗

Aspergillus nidulans as a model system to characterize the DNA damage response in eukaryotes.Semantic proximity Read ↗

Multiple roles of vertebrate REV genes in DNA repair and recombination.Semantic proximity Read ↗

A mutation in Dbf4 motif M impairs interactions with DNA replication factors and confers increased resistance to genotoxic agents.Semantic proximity Read ↗

A chemical-genetic screen to unravel the genetic network of CDC28/CDK1 links ubiquitin and Rad6-Bre1 to cell cycle progression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.