Article
RecN protein and transcription factor DksA combine to promote faithful recombinational repair of DNA double-strand breaks.
Molecular microbiology - 1 Jul 2005
Meddows Tom R, Savory Andrew P, Grove Jane I, Moore Timothy, Lloyd Robert G
Abstract excerpt
In rapidly dividing bacterial cells, the machinery for repair of DNA double-strand breaks has to contend not only with the forces driving replication and transmission of the DNA but also its transcription. By exploiting I-SceI homing endonuclease to break the Escherichia coli chromosome at one or more defined locations, we have been able to investigate how these processes are co-ordinated and repair is...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.